1) Krill Oil May Prevent Obesity
Krill oil blocks the endocannabinoid (EC) pathway, which controls appetite, promoting weight loss [R].
Mice with normal omega-3 levels have normal EC levels, while omega-3-deficient mice have higher endocannabinoid levels [R].
Krill oil raised omega-3 levels and reduced EC levels in rats [R].
Although krill oil did not affect food intake, it lowered 2-arachidonoylglycerol (2-AG), an EC involved in overeating [R, R].
Lowering EC levels reduces the likelihood of overeating, which helps prevent weight gain and obesity.
2) Krill Oil May Lower Cholesterol Levels
Krill oil reduced cholesterol in healthy rats, rats with high levels of fat in the blood, and rats fed a high-cholesterol diet [R, R].
In patients with high cholesterol, both low (1-1.5 g) and high (2-3 g) doses of krill oil decreased total cholesterol (by 13 and 18%) compared to fish oil and placebo [R, R].
3) Krill Oil Reduces Inflammation
In a study (DB-RCT) of 90 heart disease and arthritis patients, krill oil reduced C-reactive protein, a marker of inflammation [R].
Astaxanthin in krill oil blocks nitric oxide production, which reduces TNF-α production. However, astaxanthin levels in krill oil may be too low to provide health benefits [R, R, R].
Lowering these markers of inflammation helps prevent oxidative damage and excessive inflammation.
4) Krill Oil Combats Arthritis
Omega-3s from krill oil reduced inflammatory cytokine levels, which helps prevent arthritis [R].
In one study (DB-RCT) of 90 heart disease and/or arthritis patients, daily krill oil reduced pain, stiffness, and functional impairment [R].
In another study (DB-RCT) of 50 patients, krill oil improved mild knee pain and range of motion [R].
In mice genetically susceptible to arthritis, krill oil reduced arthritis symptoms and development. However, krill oil did not lower inflammatory cytokines [R].
5) Krill Oil Protects the Brain
Omega-3s from krill oil help protect the brain. DHA is essential for brain development and EPA improves behavior and mood [R].
Phospholipids from krill oil have antioxidant and anti-inflammatory properties. They reduce oxidative damage in the brain and help prevent brain disorders such as depression, schizophrenia, dementia, epilepsy, and autism [R, R].
Omega-3s in krill oil also prevent brain function decline in elderly people. In a study (DB-RT) of 45 elderly males, krill oil enhanced the function of brain areas that perform calculations and working memory tasks [R].
6) Krill Oil Improves DepressionSymptoms
Seafood consumption is associated with lower rates of depression [R].
In rats, krill oil increases brain DHA levels and lowers depression-like behaviors [R].
In a study (DB-RCT) of 70 patients, krill oil improved PMS-associated depression [R].
7) Krill Oil Protects the Heart
The omega-3s in krill oil lower the rate of heart disease [R].
Additionally, krill oil:
- Increases HDL (good) cholesterol in patients with high cholesterol [R].
- Reduces fat and cholesterol levels in patients with high cholesterol and triglycerides [R].
- Reduces blood pressure in rats with high blood pressure [R].
- Reduces total blood cholesterol in rats fed high-fat diets [R].
8) Krill Oil Helps Treat Diabetes
Krill oil reduced blood glucose levels and improved glucose tolerance and insulin sensitivity in animal studies [R, R].
Krill oil helps reduce the risk of heart attack in diabetic patients by:
- Improving blood tissue function
- Lowering C-reactive protein
- Increasing HDL (good) cholesterol [R].
In 48 participants with type 2 diabetes, krill oil reduced insulin resistanceafter four weeks [R].
9) Krill Oil Stops Cancer Cell Growth
In human cells, fatty acid extracts from krill oil stopped the growth of colorectal cancer cells [R].
Since krill oil extract kills cancer cells and is well-tolerated, it is a potential anti-cancer therapy [R].
10) Krill Oil Helps Dry Eyes
Low omega-3 intake was associated with dry eye disease (eye pain and vision loss) in a study of 32,000 women [R].
In a trial (DB-RCT) of 54 participants, krill oil reduced dry eye symptoms, inflammation, and eye redness [R].
11) Krill Oil Reduces PMS Symptoms
EPA and DHA lower PMS symptoms such as mood swings, fatigue, and depression [R].
In a study (DB-RT) of 70 women, krill oil reduced stress, depression, irritability, and use of pain relievers [R].
12) Krill Oil Reduces Colitis Symptoms
Colitis is the inflammation of all or part of the colon. By reducing inflammation, krill oil reduces colitis symptoms [R].
In rats with colitis, krill oil reduced oxidative damage and colon inflammation [R].
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