“The beneficial effects of statin drugs extend beyond the measured level of total cholesterol and other lipids such as triglycerides,” says Robert F. DeBusk, M.D., professor emeritus of cardiovascular medicine at Stanford University. “The statin drugs markedly reduce LDL and triglycerides, while increasing levels of HDL or ‘good’ cholesterol.
By comparison, DeBusk says, “The role of exercise in lowering cardiovascular risk is less well-established than the role of lipid-lowering drugs, and the effects of diet are more modest.”
Robert S. Greenfield, M.D., medical director of non-invasive cardiology and cardiac rehabilitation at MemorialCare, agrees that statins reduce cholesterol more than lifestyle changes. “Diet and weight loss can lower total cholesterol between 10 and 20 percent. But the most potent statins at their highest doses can lower cholesterol by 50 percent,” he says.
The Takeaway
Both doctors highly recommend a heart-healthy diet and regular exercise, even if you do take statins. “Patients who are significantly overweight, or eating too much saturated and trans fats, can lower their cholesterol significantly by eating a Mediterranean diet with caloric restriction and exercise,” says Greenfield.
If you choose not to take statins, what other prescription options are there? Early cholesterol medicines like bile acid sequestrants, nicotinic acid, and fibric acids also affect the liver. While they’re still available, they're in very limited use.
What raises cholesterol?
- Stress
- Depression (which also affects eating habits)
Statins or exercise for the above two?
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