"The West of Scotland Coronary Prevention Study (WOSCOPS) was the first trial to demonstrate a significant reduction in CV events with statin therapy for primary prevention. WOSCOPS randomized 6595 middle-aged men with hyperlipidemia and no previous history of MI to pravastatin or placebo. This trial demonstrated a 31% relative risk reduction of coronary events, an effect that was seen within 6 months of randomization. The absolute benefit was 2.4%; therefore, the number needed to treat was 33 patients in order to prevent one coronary event at 5 years.
In addition, it can be estimated that treating 1000 middle-aged men with hyperlipidemia and no evidence of previous MI with pravastatin for 5 years will result in 14 fewer coronary angiograms, 8 fewer revascularization procedures, 19 fewer nonfatal MIs, 7 fewer CV deaths, and 9 fewer overall deaths."
Source: https://www.wikijournalclub.org/wiki/WOSCOPS
Ohhhh...hang on, just as lifestyle changes are recommended instead of reliance on pills, this blog also encourages people to do their own research and BE CRITICAL.
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