High-fat, low-carbohydrate diet promotes arrhythmic death and increases myocardial ischemia-reperfusion injury in rats

We concluded that in vivo HFLCD does not affect nonischemic LV function but leads to greater myocardial injury during I/R, with increased risk of death by pump failure and ventricular arrhythmias, which might be associated with altered cardiac energetics, mitochondrial fission/fusion dynamics, and store-operated Ca2+ channel expression.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137127/?fbclid=IwAR1KGrqKGz81jnHvJSujAsgUhowJQX-TPhqF9aYv7DGUcP2sJFLnpOjPdbQ