Statin trials

Some say that the preponderance of statin trials has been tainted by ‘industry sponsorship’, influenced by ‘statistical deception’, and riddled with ‘flawed methodology’^[4],[5],[6].

^[4] Lundh A, Lexchin J, Mintzes B et al. Industry sponsorship and research outcome. Cochrane Database Syst Rev 2017;2:MR000033.

^[5] Diamond DA, Ravnskov U. How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease. Exp Rev Clin Pharmacol 2015;8(2):201–10. doi: 10.1586/17512433.2015.1012494

^[6] De Lorgeril M, Rabaeus M. Beyond confusion and controversy, can we evaluate the real efficacy and safety of cholesterol-lowering with statins?J Controversies Biomed Res 2015;1(1):67–92. doi: 10.15586/jcbmr.2015.11