Facts:
- More than 80% of the benefits of statins occur at the lowest dose.7
- However, it is true that more-intensive statin therapy regimens provide a greater benefit than less-intensive statin therapy, and reduce vascular events by a further 15% (95% CI 11% to 18%; P <.0001).8
In short, lipid-lowering therapy is widely available, yet underused. Pharmacists can help educate patients with the strongest available data on the benefits of these life-savings drugs.
References
7. Josan K, McAlister FA. Cholesterol lowering for secondary prevention: what statin dose should we use?. Vasc Health Risk Manag. 2007;3(5):615-627.
8. Cholesterol Treatment Trialists’ (CTT) Collaboration, Baigent C, Blackwell L, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670-1681.
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