PAD

Taking action to control your risk factors can help prevent or delay peripheral artery disease (P.A.D.) and its complications. Know your family history of health problems related to P.A.D. If you or someone in your family has the disease, be sure to tell your doctor. Controlling risk factors includes the following.
  • Be physically active.
  • Be screened for P.A.D. A simple office test, called an ankle-brachial index or ABI, can help determine whether you have P.A.D.
  • Follow heart-healthy eating.
  • If you smoke, quit. Talk with your doctor about programs and products that can help you quit smoking.
  • If you’re overweight or obese, work with your doctor to create a reasonable weight-loss plan.
The lifestyle changes described above can reduce your risk of developing P.A.D. These changes also can help prevent and control conditions that can be associated with P.A.D., such as coronary heart disease, diabetes, high blood pressurehigh blood cholesterol, and stroke.

If you have peripheral artery disease (P.A.D.), you’re more likely to also have coronary heart diseaseheart attackstroke, and transient ischemic attack ("mini-stroke"). However, you can take steps to treat and control P.A.D. and lower your risk for these other conditions.

Living With Peripheral Artery Disease Symptoms

If you have P.A.D., you may feel pain in your calf or thigh muscles after walking. Try to take a break and allow the pain to ease before walking again. Over time, this may increase the distance that you can walk without pain.
Talk with your doctor about taking part in a supervised exercise program. This type of program has been shown to reduce P.A.D. symptoms.
Check your feet and toes regularly for sores or possible infections. Wear comfortable shoes that fit well. Maintain good foot hygiene and have professional medical treatment for corns, bunions, or calluses.

Ongoing Health Care Needs and Lifestyle Changes

See your doctor for checkups as he or she advises. If you have P.A.D. without symptoms, you still should see your doctor regularly. Take all medicines as your doctor prescribes.
Heart-healthy lifestyle changes can help prevent or delay P.A.D. and other related problems, such as coronary heart disease, heart attack, stroke, and transient ischemic attack. Heart-healthy lifestyle changes include physical activityquitting smoking, and heart-healthy eating.

Clinical Trials

The National Heart, Lung, and Blood Institute (NHLBI) is strongly committed to supporting research aimed at preventing and treating heart, lung, and blood diseases and conditions and sleep disorders.
NHLBI-supported research has led to many advances in medical knowledge and care. For example, this research has uncovered some of the causes of various diseases and conditions, as well as ways to prevent, diagnose, or treat them.
The NHLBI continues to support research aimed at learning more about various diseases and conditions, including peripheral artery disease (P.A.D.). For example, NHLBI-supported research on P.A.D. includes studies that explore:
  • Ways to increase physical activity and its benefits in people who have P.A.D., such as motivational interviewing or taking nutritional supplements
  • The effectiveness of certain types of cells to improve or increase blood flow or activity level in people who have P.A.D.
  • The causes of atherosclerosis
  • The effect of short sleep duration on cardiovascular function
Much of this research depends on the willingness of volunteers to take part in clinical trials. Clinical trials test new ways to prevent, diagnose, or treat various diseases and conditions.
For example, new treatments for a disease or condition (such as medicines, medical devices, surgeries, or procedures) are tested in volunteers who have the illness. Testing shows whether a treatment is safe and effective in humans before it is made available for widespread use.
By taking part in a clinical trial, you can gain access to new treatments before they're widely available. You also will have the support of a team of health care providers, who will likely monitor your health closely. Even if you don't directly benefit from the results of a clinical trial, the information gathered can help others and add to scientific knowledge.

If you volunteer for a clinical trial, the research will be explained to you in detail. You'll learn about treatments and tests you may receive, and the benefits and risks they may pose. You'll also be given a chance to ask questions about the research. This process is called informed consent.
If you agree to take part in the trial, you'll be asked to sign an informed consent form. This form is not a contract. You have the right to withdraw from a study at any time, for any reason. Also, you have the right to learn about new risks or findings that emerge during the trial.

For more information about clinical trials related to P.A.D., talk with your doctor. You also can visit the following Web sites to learn more about clinical research and to search for clinical trials:

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